River Refresh Hypochlorous Acid Oral Rinse bottle with measuring cup on a marble countertop, featuring a soft blue background and natural greenery.

Hypochlorous Acid Mouthwash

Beyond Fresh Breath.

Freshly activated HOCl for whole-mouth care, gum health and everyday oral hygiene—without the burn.

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What Is Hypochlorous Acid Mouthwash?

Hypochlorous acid (HOCl) is an antimicrobial molecule naturally produced by your body's immune system to help fight germs. River Refresh brings this same chemistry to everyday oral care with a custom-formulated, freshly activated mouthwash. By complementing brushing and flossing with antimicrobial action, it helps reduce oral bacteria, supports gum hygiene and freshens breath—going beyond simply masking odors with mint.

Learn More About HOCl for Oral Care →
  • FIGHT ODOR-CAUSING BACTERIA

    Helps reduce oral bacteria associated with bad breath for a fresher, cleaner-feeling mouth.

  • SUPPORT GUM & ORAL HEALTH

    Complements brushing and flossing to support everyday gum care and a healthier oral-hygiene routine.

  • GENTLE WITHOUT THE BURN

    Alcohol-free, fluoride-free and unflavored, without the harsh sting or burn.

Common Uses for Everyday Oral Care

More Than Fresh Breath.

Hypochlorous acid (HOCl) helps reduce germs and odor-causing bacteria in the mouth, supporting healthier gums, everyday oral hygiene and the body's natural healing processes. From gum care and mouth irritations to oral piercings and dental appliances, River Refresh delivers gentle oral care—with fresher breath as an added benefit.

Gum Health
Mouth Irritations
Fresh Breath
Throat Care
Oral Piercings
Braces & Dental Appliances

Shop Fresh HOCl Oral Care

Hypochlorous Acid Mouthwash + Oral Rinse

Start with the 48 oz Starter Kit: a reusable mixing bottle, measuring cup and three fresh 16 oz batches of alcohol-free, fluoride-free oral rinse.

  • Reusable 16 oz mixing bottle
  • 1 oz measuring cup
  • 3 Activation Packets™ — each makes one fresh 16 oz batch
  • Oral formula: 100 ppm HOCl

Why Fresh HOCl Matters for Oral Care

When it comes to your daily oral hygiene, you want confidence in the freshness, formulation and performance of what you’re putting in your mouth.

HOCl is a powerful but sensitive antimicrobial. Exposure to heat, sunlight and air can break down HOCl, reducing its effectiveness. With premixed HOCl oral rinse, storage and shipping conditions before it reaches you aren’t always visible.

River Refresh lets you activate fresh HOCl in about 30 seconds. Each Activation Packet™ makes a fresh 16 oz batch of oral rinse, formulated at 100 ppm and a mouth-friendly pH for everyday oral care.

Read: Why Fresh Hypochlorous Acid Matters

Control Freshness. Trust Performance.™

Fresh in a Flash.™

Activate fresh HOCl in 3 simple steps.

Three-step River Refresh HOCl Oral Rinse activation: insert a whole Activation Packet into the bottle, add purified or distilled water, secure the cap and swirl.
  1. Drop

    Insert one Activation Packet™ into the 16 oz bottle.

  2. Fill

    Add distilled or purified water.

  3. Swirl

    Secure cap and swirl for 10 seconds.

Insert one Activation Packet™ into the 16 oz bottle. Add distilled or purified water. Secure cap and swirl for 10 seconds.

How to Use Hypochlorous Acid Mouthwash

Make It Part of Your Routine.

Start by brushing, flossing and cleaning your tongue to remove debris and buildup. Follow with River Refresh HOCl Oral Rinse for antimicrobial action that helps reduce oral bacteria, freshen breath and support gum health—going beyond what mechanical cleaning alone can do. No water rinse needed afterward. Just wait a few minutes before eating or drinking. Use at least twice daily and anytime you want a fresh reset.

How to Use Hypochlorous Acid Oral Rinse →

Woman swishing oral rinse as part of her daily oral hygiene routine.
Swish & Gargle Swish ½–1 oz for 30–60 seconds, gargle and spit.
Pouring oral rinse from a measuring cup into an oral irrigator reservoir.
Oral Irrigator Add fresh HOCl to the reservoir. Empty and clean after use.