Woman applying facial mist outdoors with a blurred natural background

Hypochlorous Acid

Freshly Activated

for Clean Living

River Refresh is the Clean-Care System Powered by the Freshest Hypochlorous Acid (HOCl)

Formulas for skincare, pet care and all-purpose cleaning.

Hypochlorous Acid: The River Refersh Difference

Freshness drives performance — and only River Refresh lets you control it.


Fresh hypochlorous acid (HOCl) is nature’s own defense molecule — a non-toxic, all-natural antimicrobial that neutralizes bacteria, viruses, fungi, and odor-causing microbes with precision and purity. It’s the germ-fighting warrior your skin, pet, and home deserve.

For decades, HOCl has been trusted in hospitals, veterinary clinics, agriculture, and food safety — powerful, safe, and proven. More recently, it’s become available to consumers in pre-mixed bottled solutions, but product stability and shelf life remain a challenge. This fragile molecule is sensitive to heat, light, and air, and exposure during manufacturing, storage, and shipping can erode its freshness by altering pH balance and concentration levels. With so many unknowns, its antimicrobial impact is anyone’s guess.

River Refresh changes that.

Our exclusive patent-pending Activation Packet™ lets you create HOCl on demand, so every mix delivers maximum purity and strength. This on-the-spot activation preserves the molecule’s antimicrobial power and odor-eliminating performance.

Each River Refresh formulation is uniquely balanced in pH and concentration, precisely tuned for each product line - skin care, pet care, and all-purpose cleaning. The result is targeted performance across every collection — pure, potent, and always fresh.

Learn more about how HOCl freshness and charge affect performance in our Refresh Lab article Why River Refresh HOCl is Different—and Better.

It’s science, simplified. Freshness, perfected.
When you control freshness, you can trust performance.™

Hypochlorous Acid

Product Lines

River Refresh delivers three hypochlorous acid–powered product lines, each uniquely and precisely balanced in pH and concentration to meet distinct needs.

  • Hypochlorous Skin Care – Pure, dermatologist-trusted formulas that calm, cleanse, and protect skin with clinical-grade results and everyday gentleness.
  • Hypochlorous Pet Care – Safe, non-toxic solutions that deodorize, clean, and support healthy skin and coat care for pets.
  • Hypochlorous All-Purpose Cleaner – A natural disinfectant that tackles surfaces, odors, and germs without harsh chemicals or residue.

From face to fur to every surface in between, River Refresh delivers clean, science-backed care that’s tough on microbes and gentle on everything else.

Clinically strong. Everyday gentle. Always fresh.

Hypochlorous Skincare
Woman with eyes closed misting face with River Refresh Hypochlorous Acid Face & Lash Spray

Hypochlorous Skincare

Hypochlorous Pet Care
Dog and cat laying on a couch covered by a blanket

Hypochlorous Pet Care

Hypochlorous Home Cleaning & Disinfection
Clean white kitchen counter with light coming in through window

Hypochlorous Home Cleaning & Disinfection

Hypochlorous Acid - Why Trust It?

Hypochlorous acid (HOCl) isn’t a buzzword — it’s the same molecule your white blood cells use to fight bacteria and calm inflammation. Trusted by dermatologists, veterinarians, ophthalmologists, and scientists for decades, HOCl has proven its power across wound care, skincare, veterinary medicine, eye health, and food safety.

Here’s why HOCl stands apart:

  • Natural antimicrobial: Neutralizes bacteria, viruses, and fungi without harsh chemicals or toxins.
  • Anti-inflammatory: Calms redness, irritation, and supports your body’s natural healing process.
  • pH-balanced: Gentle on skin, eyes, and pets — no sting, no residue, no drama.
  • Versatile: Our unique formulations support skincare, pet care and all-purpose cleaning because that's where germs are!
  • Eco-smart: Non-toxic, biodegradable, and environmentally safe.

Scientists unlocked this powerhouse molecule — and River Refresh ensures it activates at peak performance when you need it. Clinically proven to disinfect, deodorize, and soothe, hypochlorous acid works in harmony with your body’s natural defenses.

No fumes. No film. No worries. Just nature’s purest clean — fresh, fast, and safe for the whole family.

Trust what your body already knows: hypochlorous acid works.


Learn how HOCl fits everyday life in Hypochlorous: The Tiny Molecule Doing Big Things

Discover real-world ways to use HOCl — from skincare to kitchens — in our Refresh Lab articles